“Evolution in a Toxic World addresses the challenges posed to life on earth by a plethora of toxic threats. There are chapters dedicated to ozone, oxygen, metals, assorted chemical agents, cancer, etc. … The book serves as an excellent introduction to the topic of toxicology and evolution for the college student or general reader.”
BioScience Review by Judith S. Weis
“The book is written in an accessible style and is aimed at the general public, as well as at scientists. The third-person scientific writing is interspersed with personal anecdotes and thoughts, which should help to make the book more appealing.”
REVIEWS FROM THE REV: “Evolution in a Toxic World: How Life Responds to Chemical Threats” by Emily Monosson
“Evolution in a Toxic World” is, in some ways, a story of the evolution of one toxicologist’s personal and professional evolution in a field that is, by her account, at last merging with the insights available from the field of evolutionary studies. For it turns out that toxicology has much more to concern itself with than the occasional dramatic case of humans being poisoned by their own chemical creations. The emerging reality about the interactions of thousands upon thousands of “new” chemical compounds with the evolved biology of every living thing is an area that requires careful study and new ways of defining just what dangers might lurk in our present and future environments (as altered by human activity).
The reality is this: we industrious humans have liberated tons of heavy metals and naturally-occuring materials from the earth through our mining and burning and manufacturing. Along the way we have invented chemical compounds that have never existed in nature. It stands to reason that such an environment — changed as it is from the one we evolved in — might produce some surprises in our biology, and this is proving to be the case.
But this case is sometimes subtle and nuanced — not always a tale of deathly poisons, but often of chemicals whose molecular shapes resemble hormones, say, and that fool living cells into taking them up in ways that alters reproductive cycles or DNA.
This book is not alarmist, even if there are alarming revelations as the author takes us along on her own journey into our evolutionary past in order to better understand the task that is before scientists such as her (and humankind). it is a well-written, cogent and enjoyable book to read, well worth your time if for no other reason than the fact that you have to live your life in this new chemical world we have created.
I highly recommend this book.
Evolution in a toxic world | Book Review | Grrrl Scientist
The author investigates how from its very beginning, life evolved to deal with all sorts of toxins, a process that continues today, and she predicts what the future may hold.
Earth is a hostile place — and that’s even before one starts attending school. Even when life first sparked into being, it had to evolve defenses to deal with a number of toxins, such as damaging ultraviolet light, then there were toxic elements ranging from iron to oxygen to overcome, later, there was DDT and other toxic chemicals and of course, there are all those dreaded cancers.
In Evolution In A Toxic World: How Life Responds To Chemical Threats [Island Press; 2012: Guardian Bookshop; Amazon UK;Amazon US], environmental toxicologist Emily Monosson outlines three billion years of evolution designed to withstand the hardships of living on this deadly planet, giving rise to processes ranging from excretion, transformation or stowing harmful substances. The subtitle erroneously suggests these toxins are only chemical in nature, but the author actually discusses more than this one subclass of toxins.
The method that arose to deal with these toxins is a plethora of specialised, targeted proteins — enzymes that capture toxins and repair their damages. By following the origin and progression of these shared enzymes that evolved to deal with specific toxins, the author traces their history from the first bacteria-like organisms to modern humans. Comparing the new field evolutionary toxicology to biomedical research, Dr Monosson notes: “In light of evolution, biomedical researchers are now asking questions that might seem antithetical to medicine”. Continuing this analogy, she frames her argument thus:
“Simply put,” write Randolph Nesse and co-authors in the journal Science, “… training in evolutionary thinking can help both biomedical researchers and clinicians ask useful questions that they might not otherwise pose.” The same could be said for researchers and practitioners of toxicology. [p. 3]